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MASH-TAG 2027 Agenda

January 7-9
@ The Chateaux Deer Valley

7815 Royal Street East,
Park City, Utah

(Mountain Standard Time)

Thursday, January 7th, 2027

All Day Arrivals

6:00 PM - 7:30 PM

Course Directors' Reception

Friday, January 8th, 2027

6:45 AM - 7:45 AM

Breakfast

7:45 AM - 8:10 AM

The Year in Review

SESSION 1: New and Emerging Data from 2026

8:15 AM - 8:35 AM

Lanifibranor Data

8:35 AM - 8:55 AM

PNPLA3, HSD17B13 and Other Genetic Targets in MASH

8:55 AM - 9:15 AM

GLP-1 and Glucagon and/or GIP: Now and What's To Come

9:15 AM - 9:35 AM

A Deep Dive into Landscape of Thyroid Hormone Beta Receptor Agonists

9:35 AM - 9:50 AM

FGF21 as a Class: Recent Developments/Updates

9:50 AM - 10:10 AM

Panel Discussion

10:10 AM - 10:30 AM

Break - Exhibit Hall/Poster Viewing

SESSION 2: Challenges in Drug Development including Pediatrics

10:30 AM - 10:45 AM

Where are we with Pharmacologic Interventions in Pediatric MASH?

10:45 AM - 11:00 AM

Specifics of Trial Design and Outcome Assessment in Children

11:00 AM - 11:15 AM

Heritability of MASLD and Genetics Approaches in MASLD

11:15 AM - 11:30 AM

New Insights into Event Rates for MALO in F4c

11:30 AM - 11:45 AM

Panel Discussion

11:45 AM - 11:55 AM

Oral Abstract Presentation

11:55 AM - 12:05 PM

Oral Abstract Presentation

12:05 PM - 1:15 PM

CME Symposium - Tentative

1:15 PM - 4:00 PM

Meetings, Poster Viewing and Self-Directed Learning

SESSION 3: Muscle and Bone as the Newest Disrupters in the MASLD Drug Landscape

4:00 PM - 4:20 PM

Strategies for Muscle Preservation with Incretin Therapies

4:20 PM - 4:40 PM

Bone Health and Weight Losing Agents

4:40 PM - 5:00 PM

Sarcopenic Obesity: How to Diagnose and Why Should We Care?

5:00 PM - 5:20 PM

Myokine Signaling in Adipose Tissue: A New Target for MASLD?

5:20 PM - 5:35 PM

Panel Discussion

5:35 PM - 5:55 PM

Break

SESSION 4: Trial Considerations in Advanced Chronic Liver Disease

5:55 PM - 6:15 PM

HCC: A Blind Spot in MASLD Trials

6:15 PM - 6:35 PM

Cell Free DNA Based Biomarkers in MASH, Cirrhosis and HCC

6:35 PM - 6:55 PM

Mechanisms of Hepatic Carcinogenesis in MASLD

6:55 PM - 7:15 PM

Debate: Should We Include Recompensated MASH Cirrhosis Patients in Cirrhosis Trials?

7:15 PM - 7:30 PM

Panel Discussion

7:30 PM

Stephen A. Harrison Award for Excellence in MASH

7:30 PM

Faculty Dinner

Saturday, January 9th, 2027

6:45 AM - 8:00 AM

Breakfast

SESSION 5: Expanding Horizons: Extra Hepatic Considerations in MASLD

8:00 AM - 8:20 AM

Uncoupling of Fat and Lean Mass Loss During GLP-1 Induced Weight Reduction

8:20 AM - 8:40 AM

Liver and Healthy Aging and Longevity

8:40 AM - 9:00 AM

MASLD and Kidney Disease - a Reno-Hepatic Axis?

9:00 AM - 9:20 AM

MASLD and Heart Disease: Does a Fatty Liver Lead to a Broken Heart?

9:20 AM - 9:35 AM

Panel Discussion

9:35 AM - 9:50 AM

Break

SESSION 6: Statistical and Methodological Considerations for Clinical Trials

9:50 AM - 10:10 AM

Assessing Outcomes: Ordinal Outcomes Estimands, Imputation Methods and Missing Data

10:10 AM - 10:30 AM

Emulation Trials and Observational Data: Can They Be Trusted When RCTs Are Not Feasible?

10:30 AM - 10:50 AM

Statistical Genetics and Prediction of Drug Efficacy (A Tool for Predictive Medicine)

10:50 AM - 11:10 AM

Assessing Responders Non-Invasively: What Would it Take in 2026?

11:10 AM - 11:25 AM

Panel Discussion

11:25 AM - 11:45 AM

Case Based Patient Journey: Nuances in Management

11:45 AM - 11:55 AM

Oral Abstract Presentation

11:55 AM - 12:05 PM

Oral Abstract Presentation

12:05 PM - 12:25 PM

How to Approach Two Approved Therapies: Step Up, Top Down or Tango?

12:25 PM - 4:00 PM

Meetings, Poster Viewing and Self-Directed Learning

SESSION 7: Emerging Science

4:00 PM - 4:20 PM

The Biology of Lipid Droplets and the Pathobiology of Steatohepatitis

4:20 PM - 4:40 PM

GDF15, an Emerging Metabolic Messenger

4:40 PM - 5:00 PM

Harnessing Glucagon Biology for the Treatment of MASLD

5:00 PM - 5:20 PM

The CAR-T Cell Promise for the Treatment of Liver Fibrosis

5:20 PM - 5:35 PM

The Top 5 Basic Papers of 2026

5:35 PM - 5:50 PM

Panel Discussion

5:50 PM - 6:05 PM

Break

SESSION 8: New Pharmacological Targets and Approaches to Approval

6:05 PM - 6:15 PM

Eloralintide

6:15 PM - 6:25 PM

Cagrilintide

6:25 PM - 6:35 PM

Modulating HSD17B13 for Therapeutic Intervention

6:35 PM - 6:45 PM

CIDEB and PNPLA3

6:45 PM - 6:55 PM

The Promise of Oral GLP-1 Agonists

6:55 PM - 7:05 PM

Panel Discussion

7:05 PM

Wrap-Up

Links

Event Info

Elm Planning

Event Email

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